Evolution and Health: A Conversation with Evolutionary Geneticist Dr. Dan Janes on the Occasion of Charles Darwin’s Birthday

Today, February 12, is Darwin Day—an occasion to recognize the scientific contributions of 19th-century naturalist Charles Darwin. In this video, our own evolutionary geneticist, Dan Janes, answers questions about Darwin and the role of evolution in health and biomedicine.

For more details about evolution and you, check out our articles Evolution and Health and Everyday Evolution.

A Heart-Shaped Protein

Structure of the serum albumin protein

The structure of the serum albumin protein is shaped like a heart. Credit: Wladek Minor, University of Virginia.

From cookies and candies to balloons and cards, heart-shaped items abound this time of year. They’re even in our blood. It turns out that the most abundant protein molecule in blood plasma—serum albumin (SA)—is shaped very much like a heart. Continue reading

Cryo-Electron Microscopy Reveals Molecules in Ever Greater Detail

The molecular visualization technique known as cryo-electron microscopy (cryo-EM) was recently named the “2015 Method of the Year” by the journal Nature Methods. In a recent blog post, NIH Director Francis Collins explains how the technology works and just how rapidly it has advanced. He writes, “Today’s cryo-EM is so powerful that researchers can almost make out individual atoms!” He also notes, “These dramatic advances serve as a reminder of the ways in which basic technological innovation can open new realms of scientific possibility.”

We fund many scientists who are developing and applying cryo-EM to bring the details of biological structures into unprecedented focus. Here are two examples of their work and its potential impact. Continue reading