The tiny roundworm Caenorhabditis elegans is one of the most common research organisms—creatures scientists use to study life. While C. elegans may seem drastically different from humans, it shares many genes and molecular pathways with us. Viewed with a microscope, the worm can also be surprisingly beautiful. Aside from the stunning imagery, these examples from our Image and Video Gallery show how C. elegans helps scientists advance our understanding of living systems and find new ways to improve our health.
Credit: Keir Balla and Emily Troemel, University of California San Diego.
This C. elegans has been infected with microsporidia (purple), parasites closely related to fungi. The yellow shapes are the worm’s gut cells, and the blue dots are nuclei. Some microsporidia can infect people, so studying the parasites in worms could help researchers devise strategies to prevent or treat infections.
Continue reading “Cool Images: Wondrous Worms”
NIGMS, in collaboration with Scholastic, has developed a collection of free biology and health activities on the educational app Kahoot! You can play them alone, with friends, or with a class of students. Four Kahoots! are currently available:
Continue reading “Engage Learners in Science and Health With Our Kahoots!”
A cross-section of a cell showing organelles. Credit: Judith Stoffer.
Welcome to our tour of the cell! Imagine you’ve shrunk down to about 3 millionths of your normal size. You are now about 0.5 micrometers tall (a micrometer is 1/1,000th of a millimeter). At this scale, a medium-sized human cell looks as long, high, and wide as a football field. But you can’t see nearly that far. Clogging your view is a rich stew of molecules, fibers, and various cell structures called organelles. Like the internal organs in your body, organelles in the cell each have a unique biological role to play.
The Nucleus and Its Closest Neighbor
Our first stop is the somewhat spherical structure about 50 feet in diameter. It’s the nucleus—basically the cell’s brain. The nucleus is the most prominent organelle and can occupy up to 10 percent of the space inside a cell. It contains the equivalent of the cell’s genetic material, or DNA.
Continue reading “Take a Tour of Your Cells’ Organelles!”
Proteins play a role in virtually every activity in the body. They make up hair and nails, help muscles move, protect against infection, and more. Many NIGMS-funded researchers study the rich variety of proteins in humans and other organisms to shed light on their roles in health and disease.
Take our quiz to test how much you know about proteins. Afterward, find more quizzes and other fun learning tools on our activities and multimedia webpage, which includes an interactive protein alphabet.
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Cover of Pathways
NIGMS and Scholastic bring you our latest issue of Pathways, which focuses on imaging tools that help scientists unlock the mysteries of our cells and molecules. A better understanding of this tiny world can help researchers learn about the body’s normal and abnormal processes and lead to more effective, targeted treatments for illnesses.
Pathways is designed for students in grades 6 through 12. This collection of free resources teaches students about basic science and its importance to health, as well as exciting research careers.
Continue reading “Pathways: The Imaging Issue”
We seldom see microscopic objects next to one another, so it can be difficult to picture how they compare. For instance, it might surprise you that a thousand cold-virus particles could line up across one human skin cell! The largest objects that scientists view through microscopes are about a millimeter (roughly the size of a poppyseed), and they’re about 10 million times larger than the smallest molecules scientists can view: atoms.
Continue reading “Through the Looking Glass: Microscopic Structures in Many Sizes”
Some bacteria benefit us as part of our microbiome—the vast collection of microorganisms that live in and on our bodies—while others can make us sick. Whether helpful or dangerous, bacteria can appear colorful and striking under a microscope. These photos provide just a small peek into the incredible diversity of these microbes.
Credit: Liyang Xiong and Lev Tsimring, BioCircuits Institute, UCSD.
This floral pattern emerged when a researcher grew two strains of bacteria—Acinetobacter baylyi (red) and Escherichia coli (green)—together for 2 days in a petri dish. A. baylyi are found in soil and typically don’t pose a threat to humans, although some strains can cause infections. E. coli normally live in the intestines of people and animals. Most strains are harmless, but some can cause food poisoning or other illnesses.
Continue reading “Cool Images: Bewitching Bacteria”
Cells are the smallest units of life, providing structure and function for all living things, from microorganisms—like bacteria, algae, and yeast—to humans. They come in a wide range of sizes and shapes, and they’re complex machines with many smaller components that work together.
Some NIGMS-funded researchers use imaging techniques to peer inside cells, examine their structures, and study how they divide, grow, communicate, and carry out basic functions. Others use biochemical and genetic tests to study how cells interact with their environments, including those that may be toxic. Understanding cells’ biological processes helps to keep us healthy and identify new methods for treating disease.
Take our quiz to test how well you know cells. Afterward, check out our Studying Cells fact sheet and other blog posts on cell biology.
Continue reading “Quiz: How Does Your Knowledge of Life’s Building Blocks Stack Up?”
If you’re looking for ways to engage students in science this school year, NIGMS offers a range of free resources that can help. All of our STEM materials are online and print-friendly, making them easy to use for remote teaching.
Pathways , developed in collaboration with Scholastic, is aligned with STEM and ELA education standards for grades 6 through 12. Materials include:
- Student magazines with corresponding teaching guides
- Related lessons with interactives
- Vocabulary lists
Cover of Pathways
student magazine, third issue.
Available lessons examine basic science careers, regeneration, and circadian rhythms.
Continue reading “Explore Our STEM Education Resources for the New School Year”
Wildlife photos can be truly stunning, and cute cat pictures are a cornerstone of the internet. But zooming in on the early lives of fish, insects, and worms can have equally wonderful results. Using powerful microscopes, researchers are revealing the complexity and beauty of animal development.
Credit: James E. Hayden, The Wistar Institute, Philadelphia, PA.
This image captures the spiral-shaped ovary of an anglerfish in cross section. Once matured, these eggs will be released in a gelatinous, floating mass. For some species of anglerfish, this egg mass can be up to 3 feet long and include nearly 200,000 eggs.
Continue reading “Cool Images: Animal Development in Progress”