“You’re doing something really important with people who are important to you,” Paul Worsley remarks when asked about having his younger brothers Caleb and Adam as lab mates. The trio are undergraduate students working in the lab of Santimukul Santra, Ph.D., at Pittsburg State University in Pittsburg, Kansas.
All three brothers are part of the Kansas IDeA Networks of Biomedical Research Excellence (K-INBRE). Paul is currently a junior majoring in biology and history. He plans to go to medical school when he graduates, but his time in the lab has given him a love for research—and has even led him to toy with the idea of going to graduate school instead. His twin brothers Caleb and Adam are only freshmen, but they both think they want to pursue scientific research when they graduate.
When Paul was a sophomore, he applied for a K-INBRE research spot in Dr. Santra’s lab and was immediately accepted. He quickly realized that organic chemistry in the lab was much different—and more exciting—than anything he’d seen in the classroom. “I like organic synthesis because it really tests your knowledge,” he says. “Answering exam questions is way different than actually doing it in a lab.” Despite the challenges that came with research, Paul was clearly doing great work because one day Dr. Santra joked, “Hey, you got any brothers?” Paul responded, “Actually, yes.”
Attention, educators! We’re announcing a new clearinghouse of free STEM education resources covering a wide range of health and biomedical research topics for students in grades K through 12. The STEM teaching resources website provides links to great content from various institutes and centers within NIH, as well as materials developed under the NIGMS Science Education Partnership Award program.
The resources are easy to navigate within the following subject areas:
The cloud. To many, it’s a mysterious black hole that somehow transports photos and files from their old or lost phone to their new one. To some researchers, though, it’s an invaluable resource that allows them access to data analytics tools they wouldn’t otherwise have.
Scientists have begun using cloud computing to store, process, and analyze their data through online bioinformatics tools. Biological data sets are often large and hard to interpret, requiring complex calculating instructions—or algorithms—to understand them. Fortunately, these algorithms can run on local computers or remotely through cloud computing.
One advantage of cloud-based programs over local computers is the ability to analyze data without taking up the user’s personal storage space. With cloud-based storage, researchers can store their large data files, including their labeled notes called annotations. Another benefit is that users have easy access to software packages within the cloud for data analysis. The cloud also encourages collaboration among scientists by making it easy to share large amounts of data.
Have you ever wondered how research works? How scientists make discoveries about our health and the world around us? Whether they’re studying plants, animals, humans, or something else in our world, they follow the scientific method. But this method isn’t always—or even usually—a straight line, and often the answers are unexpected and lead to more questions. Let’s dive in to see how it all works.
Protein Data Bank’s 50 years logo. Credit: PDB website.
The Protein Data Bank (PDB), established in 1971, is the single global repository for 3D structural data of proteins, DNA, RNA, and even complexes these biological molecules form with drugs or other small molecules. More than 1 million people—including researchers, medical professionals, educators, and students—use the PDB each year. NIGMS and other parts of NIH have helped fund this free digital resource since 1978.